2,791 research outputs found
Symmetric Tensor Decomposition Description of Fermionic Many-Body Wavefunctions
The configuration interaction (CI) is a versatile wavefunction theory for
interacting fermions but it involves an extremely long CI series. Using a
symmetric tensor decomposition (STD) method, we convert the CI series into a
compact and numerically tractable form. The converted series encompasses the
Hartree-Fock state in the first term and rapidly converges to the full-CI
state, as numerically tested using small molecules. Provided that the length of
the STD-CI series grows only moderately with the increasing complexity of the
system, the new method will serve as one of the alternative variational methods
to achieve full-CI with enhanced practicability.Comment: 10 pages, 6 figure
Regulatory Reform in the Intercity Bus Industry
This Article will analyze the economic structure of the intercity bus industry and the type of service received by the public under the present regulatory scheme. It will then discuss what regulatory reforms could improve service, how these issues are addressed in the recent House-passed bill, and what further legislative reforms should be made
Alien Registration- Hitchcock, John F. (Presque Isle, Aroostook County)
https://digitalmaine.com/alien_docs/33449/thumbnail.jp
Ex-gays? A Longitudinal Study of Religiously Mediated Change in Sexual Orientation (Book Review)
Reviewed Title:
Jones, Stanton L. and Mark A. Yarhouse. Ex-gays? A Longitudinal Study of Religiously Mediated Change in Sexual Orientation. Downers Grove, IL: InterVarsity Press, 2007, 414pp. ISBN 978-0-8308-2846-3
Progranulin regulates neurogenesis in the developing vertebrate retina
We evaluated the expression and function of the microgliaâspecific growth factor, Progranulinâa (Pgrnâa) during developmental neurogenesis in the embryonic retina of zebrafish. At 24 hpf pgrnâa is expressed throughout the forebrain, but by 48 hpf pgrnâa is exclusively expressed by microglia and/or microglial precursors within the brain and retina. Knockdown of Pgrnâa does not alter the onset of neurogenic programs or increase cell death, however, in its absence, neurogenesis is significantly delayedâretinal progenitors fail to exit the cell cycle at the appropriate developmental time and postmitotic cells do not acquire markers of terminal differentiation, and microglial precursors do not colonize the retina. Given the link between Progranulin and cell cycle regulation in peripheral tissues and transformed cells, we analyzed cell cycle kinetics among retinal progenitors following Pgrnâa knockdown. Depleting Pgrnâa results in a significant lengthening of the cell cycle. These data suggest that Pgrnâa plays a dual role during nervous system development by governing the rate at which progenitors progress through the cell cycle and attracting microglial progenitors into the embryonic brain and retina. Collectively, these data show that Pgrnâa governs neurogenesis by regulating cell cycle kinetics and the transition from proliferation to cell cycle exit and differentiation. © 2017 The Authors. Developmental Neurobiology Published by Wiley Periodicals, Inc. Develop Neurobiol 77: 1114â1129, 2017Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138360/1/dneu22499.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138360/2/dneu22499_am.pd
Materiales y tecnologĂas en la Arquitectura Modernista: casos de estudio de decoraciĂłn de fachadas en Italia, Portugal y Polonia persiguiendo una restauraciĂłn racional
The results of a diagnostic survey on the materials of representative Art Nouveau buildings in Italy, Portugal and Poland are here presented and compared, as a contribution to their understanding and, hence, to support compatible restoration. In particular, the facade decorations were investigated for the appraisal of their materials and technologies, often neglected in current maintenance/restoration works and so cancelled, leading to a severe loss in architectural image. The ongoing diagnostic campaign, in collaboration among different universities, is aimed to set up a database on materials and technologies of Art Nouveau facade decorations at a European scale, as a technical-scientific background for the highlighting of preservation guidelines
Dynamic expression of the basic helix-loop-helix transcription factor neuroD in the rod and cone photoreceptor lineages in the retina of the embryonic and larval zebrafish
NeuroD is a basic helix-loop-helix (bHLH) transcription factor critical for determining neuronal cell fate and regulating withdrawal from the cell cycle. We showed previously that, in goldfish, neuroD is expressed in the rod photoreceptor lineage, and we inferred that neuroD is also expressed in a subset of amacrine cells and nascent cone photoreceptors. Here we extended that study by examining the temporal and spatial expression pattern of neuroD in the embryonic and larval zebrafish and by identifying the cell types that express this gene. NeuroD expression in the developing zebrafish retina is dynamic, spanning early retinogenesis and the maturation of cone photoreceptors. In early retinogenesis neuroD expression expands from a small patch in the ventronasal retina, through the remaining retinal neuroepithelium. As retinogenesis progresses, neuroD expression becomes restricted to amacrine cells, immature cones, and cells of rod and cone lineages. This expression achieves an adult pattern by 96 hours postfertilization (hpf), whereupon the temporal pattern of neuroD expression in central retina is spatially recapitulated at the germinative margin. The cellular pattern of expression suggests that neuroD regulates aspects of rod and cone genesis, but through separate cellular lineages. Furthermore, neuroD is coexpressed with the cone-rod-homeobox transcription factor (Crx) in putative cone progenitors and nascent cone photoreceptors, suggesting that, in the zebrafish retina, as in other vertebrate retinas, similar genetic cascades regulate photoreceptor genesis and maturation. J. Comp. Neurol. 501:1â12, 2007. © 2007 Wiley-Liss, Inc.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/55874/1/21150_ftp.pd
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